| Time | Session |
|---|---|
Buenos Aires Room – 5th Floor | |
| 12:00pm 1:00pm | IFSI Board Meeting- Lunch |
| 1:00pm 2:50pm | IFSI Board Meeting |
Grand Ballroom ABCD – 5th Floor | |
| 3:00pm 3:10pm | Welcome & Introduction: overview on SIGsChair: Yozo Ishiuji, MD Speaker: Sonja Ständer, MD |
| 3:10pm 3:45pm | IDEOM initiative New Definition of IcthChair: Gil Yosipovitch, MD Speaker: Sonja Ständer, MD |
| 3:45pm 4:20pm | Neuropathic Pruritus – Definition of BRP and NPChair: Laurent Misery, MD, PhD Speaker: Brian S. Kim, MD, MTR |
| 4:20pm 4:55pm | Chronic Prurigo Nodularis – do we really have two terms?Chair: Sarina Elmariah, MD, PhD, MPH Speaker: Martin Metz, MD |
| 4:55pm 5:00pm | Wrap UpChairs: Sonja Ständer, MD; Gil Yosipovitch, MD Speaker: Jacek C. Szepietowski, MD, PhD, FRCP |
| 5:30pm 5:45pm | Opening Ceremony Chairs: Gil Yosipovitch, MD; Elke Weisshaar, MD |
| 5:45pm 6:10pm | Bernhard Lecture Itch: From Patient Suffering to Intimate Relationship Between Cells Chairs: Gil Yosipovitch, MD; Elke Weisshaar, MD Speaker: Laurent Misery, MD, PhD |
| 6:10pm 6:30pm | Kuraishi Lecture Life’s an itch Chairs: Gil Yosipovitch, MD; Elke Weisshaar, MD Speaker: Ethan Lerner, MD, PhD |
| 6:30pm 6:45pm | IFSI AwardsChairs: Gil Yosipovitch, MD; Elke Weisshaar, MD |
Pool Deck – 7th Floor – JW Marriott | |
| 6:45pm 8:45pm | Reception |
| Time | Session |
|---|---|
| 6:30am 8:00am | Breakfast – 5th Floor |
Grand Ballroom ABCD – 5th Floor | |
| 7:00am 7:50am | Advancing Therapeutic Options Industry Session Sponsored by: Abbvie Speaker: Jonathan Silverberg, MD, PhD, MPH |
Grand Ballroom ABCD – 5th Floor | |
| 8:00am 9:00am | Plenary Session |
| 8:00am 8:20am | Imaging cortical and spinal neuronal activity in the awake, behaving animal Speaker: Allan Basbaum, PhD, FRS |
| 8:20am 8:30am | C-fibres Conspire in the Joy of Scratching an Itch Speaker: Francis McGlone, PhD |
| 8:30am 8:40am | PIEZO ion channels in mechanically evoked scratching Speaker: Rose Z. Hill, PhD |
| 8:40am 8:50am | Peripheral Mechanisms of Opioid Itch Speaker: Xinzhong Dong, PhD |
| 8:50am 9:00am | Q&ASpeakers: All |
| 9:00am 9:45am | Plenary Session |
| 9:00am 9:12am | Canine atopic dermatitis: a useful tool for advancement of One Health approach Speaker: Frane Banovic, DVM, PhD, DECVD |
| 9:12am 9:24am | Transcriptomic Profiling of Feline and Canine Sensory Ganglia – What Do We Learn About Pruriceptive Signaling?Speaker: Chie Tamamoto-Mochizuki, DVM, PhD |
| 9:24am 9:36am | Identification of pruriceptive somatosensory neurons in pigs using snRNAseq Speaker: Hans Jürgen Solinski, PhD |
| 9:36am 9:45am | Q&A Speakers: All |
Buenos Aires Room – 5th Floor | |
| 9:45am 10:15am | Break & Poster Session 1 |
| 09:50am | Staphylococcus aureus virulence factors stimulate mouse cutaneous pruriceptive C-fibers terminals Speaker: Danica Jurcakova, PhD |
| 09:55am | Transcriptomic characterization of chronic scratch lesions Speaker: Hei Sung Kim, MD, PhD |
| 10:00am | An atopic dermatitis mouse model reveals utility for comorbid depression circuitry studies Speaker: Ian McConnell, BA |
| 10:05am | Brain neurosteroids as endogenous modulators of itch in atopic dermatitis mice Speaker: Masanori Fujii, PhD |
| 10:10am | Thermal Hyperalgesia and Mechanical Allodynia in Itch Sensation: Involvement of TRPA1 Channel Speaker: Merab G. Tsagareli, PhD, DSc |
Grand Ballroom ABCD – 5th Floor | |
| 10:15am 11:00am | Concurrent Session: Clinical Atopic Dermatitis |
| 10:15am 10:27am | Anti-IL-31 Receptor Antibody in Atopic Dermatitis in Japan Speaker: Kenji Kabashima, MD, PhD |
| 10:27am 10:39am | Efficacy and safety of biologic therapies for itch in AD >Speaker: Jonathan Silverberg, MD, PhD, MPH |
| 10:39am 10:51am | Somatosensory adaptation to acute stress is altered in patients with atopic dermatitis Speaker: Macarena Tejos-Bravo, PhD |
| 10:51am 11:00am | Q&A Speakers: All |
Grand Ballroom EFG – 5th Floor | |
| 10:15am 11:00am | Concurrent Session: Basic Biomarkers |
| 10:15am 10:27am | A Class of Phosphomonoester Drugs Induces Itch through MRGPRX4 Speaker: Daphne Chien |
| 10:27am 10:39am | Targeting epidermal and neuronal TRPV4 to alleviate acute and chronic itch Speaker: Yong Chen, PhD |
| 10:39am 10:51am | TSLP instructs dendritic cells to prime IL-31 producing TH2 cells promoting pruritus and granulocytic inflammation Speaker: Bernhard Homey, MD, PhD |
| 10:51am 11:00am | Q&A Speakers: All |
Grand Ballroom ABCD – 5th Floor | |
| 11:05am 11:50am | Concurrent Session: Clinical Prurigo Nodularis |
| 11:05am 11:20am | Treatment targets and trials in prurigo Speaker: Sonja Ständer, MD |
| 11:20am 11:32am | Neuroimmune gene signature of prurigo nodularis compared to psoriasis and atopic dermatitis Speaker: Hannah Corman, BS |
| 11:32am 11:44am | Expression of phosphorylated JAK1, ERK1/2, and Akt in prurigo nodularis lesions Speaker: Takashi Hashimoto, MD, PhD |
| 11:44am 11:50am | Q&A Speakers: All |
| 11:45am 1:15pm | Lunch – 5th Floor |
Grand Ballroom EFG – 5th Floor | |
| 11:05am 11:50am | Concurrent Session: Basic Imaging |
| 11:05am 11:17am | Nanostring Imaging and Itch Speaker: Nicholas West, PhD |
| 11:17am 11:29am | Neural Oscillation Associated with Contagious Itch in Patients with Atopic Dermatitis Speaker: Younbyoung Chae, MBBS, FRCP, MRCPS, FAMS |
| 11:29am 11:41am | Scratch-AID: A deep-learning based system for automatic detection of mouse scratching behavior Speaker: Huasheng Yu, PhD |
| 11:41am 11:50am | Q&A Speakers: All |
Grand Ballroom ABCD – 5th Floor | |
| 12:05pm 12:55pm | Targeting IL-13: Does it Scratch the Itch in Atopic Dermatitis? Lunch Symposium Sponsored by Eli Lilly Speakers: Sarina Elmariah, MD, PhD, MPH; Ethan Lerner, MD,PhD |
Grand Ballroom EFG – 5th Floor | |
| 12:05pm 12:55pm | Emerging Pathways in Itch Industry Session Sponsored by Galderma Speakers: Shawn Kwatra, MD; Brian S. Kim, MD, MTR; Bernhard Homey, MD, PhD |
Grand Ballroom ABCD – 5th Floor | |
| 1:00pm 2:00pm | Plenary Session |
| 1:00pm 1:12pm | Neuroimmune regulation of itch Speaker: Brian S. Kim, MD, MTR |
| 1:12pm 1:24pm | Mechanisms of Chronic Itch in a Mouse Model of Cutaneous T Cell Lymphoma (CTCL) Speaker: Ru-Rong Ji, PhD |
| 1:24pm 1:36pm | Microbes and itch: Staphylococcus aureus induces itch and skin damage through a V8 protease-PAR1 axis Speaker: Isaac M. Chiu, PhD |
| 1:36pm 1:48pm | Neuroimmune circuits initiating allergic immunity Speaker: Caroline Sokol, MD, PhD |
| 1:48pm 2:00pm | Q&A Speakers: All |
Buenos Aires Room – 5th Floor | |
| 2:00pm 2:15pm | Break & Poster Session 2 |
| 2:05pm | Allergen sensitization status stratifies IL-31 production by memory T cells in atopic dermatitis Speaker: Luis F. Santamaria-Babí, PhD |
| 2:10pm | MRPGRX2 Antagonist EP262 Prevents Disease in a Mouse Model of Atopic Dermatitis Speaker: Veena Viswanath |
Grand Ballroom ABCD – 5th Floor | |
| 2:15pm 3:50pm | Concurrent Session: Clinical Itch and Systemic Diseases |
| 2:15pm 2:25pm | Pathophysiology of hepatic itch Speaker: Andreas Kremer, MD, PhD |
| 2:25pm 2:35pm | Burden of Itch and Treatment in Adult Patients Speaker: Cynthia Levy, MD |
| 2:35pm 2:45pm | New Treatments for Childhood Hepatic Itch: IBAT inhibitors Speaker: Binita M. Kamath, MBBChir |
| 2:45pm 2:55pm | Neurophysiological changes in patients with chronic hepatic pruritus Speaker: Miriam M. Düll, MD |
| 2:55pm 3:00pm | Q&A Speakers: All |
| 3:00pm 3:12pm | Uremic Pruritus as a model for patient involvement, patient reported outcomes Speaker: Michael Germain, MD |
| 3:12pm 3:22pm | Pathogenetic factors of chronic itch in renal transplant recipients Speaker: Jacek C. Szepietowski, MD, PhD, FRCP |
| 3:22pm 3:32pm | Q&A Speakers: All |
| 3:36pm 3:50pm | The significance of itch in chronic urticaria Chair & Speaker: Martin Metz, MD |
Grand Ballroom EFG – 5th Floor | |
| 2:15pm 3:50pm | Concurrent Session: Basic on DRG, Spinal and Brain Itch |
| 2:15pm 2:27pm | A population view of the spinal neurons that encode itch Speaker: Sarah E. Ross, PhD |
| 2:27pm 2:39pm | Asymmetric role of the lateral habenula in controlling itch sensation and behavior Speaker: Suna L. Cranfill, BS |
| 2:39pm 2:51pm | Neuromodulation beyond itch is blocked by targeting IL-13Rα1 with eblasakimab Speaker: Ferda Cevikbas,PhD |
| 2:51pm 3:03pm | Targeting TRPC4 and other TRP channels for psoriasiform itch relief Speaker: Temugin Berta, PhD |
| 3:03pm 3:15pm | Activation of NPY2R-expressing amygdala neurons inhibits itch behavior in mice without lateralization Speaker: Darya Pavlenko, MS |
| 3:15pm 3:27pm | Regional Differences in Itch Transmission Speaker: Liang Han, PhD |
| 3:27pm 3:50pm | Q&A Speakers: All |
Buenos Aires Room – 5th Floor | |
| 3:50pm 4:20pm | Break & Poster Session 3 |
| 3:55pm | Uncovering the role of Nav1.9 in itch Speaker: Wayra Brackx, MSc |
| 4:00pm | Dominant impact of IL-4/IL-13 versus IL-31 in neuroimmune mechanisms in murine models Speaker: Mithilesh Kumar Jha, PhD |
| 4:05pm | Possible association of IL-31/IL-31RA signaling and basophils with itch in porokeratosis Speaker: Satoshi Okuno, MD |
| 4:10pm | Deciphering the possible involvement of Merkel cells in the induction of alloknesis Speaker: Christelle Le Gall-Ianotto, PhD |
Grand Ballroom ABCD – 5th Floor | |
| 4:20pm 5:20pm | IFSI General Assembly |
Offsite – Buses will depart from 12th Street at 6:30pm | |
| 7:00pm 11:00pm | Social Event |
| Time | Session |
|---|---|
| 6:30am 8:00am | Breakfast – 5th Floor |
Grand Ballroom ABCD – 5th Floor | |
| 7:00am 7:50am | Mastering Itch in Atopic Dermatitis: From Neuroimmune Mechanisms to Clinical Considerations Industry Session Sponsored by: PfizerSpeakers: Shawn Kwatra, MD; Sarina Elmariah, MD, PhD, MPH |
Grand Ballroom ABCD – 5th Floor | |
| 8:00am 9:00am | Plenary Session Chairs: Matthias Ringkamp, MD, PhD; Alan Fleischer, MD |
| 8:00am 8:15am | Human experimental surrogate models of itch and pain Speaker: Lars Arendt-Nielsen, DMSc., PhD |
| 8:15am 8:30am | What’s New: Monitoring Itchy Patients Speaker: Dina Katabi, PhD |
| 8:30am 8:45am | AI – Enabled Advanced Wearables for Itch: Monitoring and Biofeedback Speaker: Steve Xu, MD, FAAD |
| 8:45am 9:00am | Challenges in Managing Itch in Pediatric Skin Diseases Speaker: Amy Paller, MD, MS |
Buenos Aires Room – 5th Floor | |
| 9:00am 9:15am | Break & Poster Session 4 |
| 9:05am | Itch is strongly associated with inguino-crural disease in hidradenitis suppurativa Speaker: Winston Liu, PhD |
| 9:10am | Itch in Aquagenic Pruritus: A patient’s perspective Speaker: Georgia Biazus Soares, BSc |
Grand Ballroom ABCD – 5th Floor | |
| 9:15am 9:55am | Concurrent Session: Clinical Psoriasis |
| 9:15am 9:25am | What’s New In Psoriatic Itch Speaker: Jacek C. Szepietowski, MD, PhD, FRCP |
| 9:25am 9:35am | Genetic dissection of defensin signaling in psoriatic inflammation and itch Speaker: Xintong Dong, PhD |
| 9:35am 9:45am | The cellular and molecular basis of psoriatic itch and inflammation Speaker: Joshua Wheeler, PhD |
| 9:45am 9:55am | Q&A Speakers: All |
Grand Ballroom EFG – 5th Floor | |
| 9:15am 9:55am | Concurrent Session: Basic Psych |
| 9:15am 9:25am | Psychodynamic aspects of itch treatment – the clinical perspective Speaker: Uwe Gieler, MD |
| 9:25am 9:35am | Effects of psychological interventions in the treatment of chronic itch: A meta-analysis Speaker: Christina Schut, PhD |
| 9:35am 9:45am | Influence of negative expectancies on itch – related avoidance behavior Speaker: Antoinette I.M. van Laarhoven, PhD |
| 9:45am 9:55am | Q&A Speakers: All |
Grand Ballroom ABCD – 5th Floor | |
| 10:00am 10:55am | Concurrent Session: Neuropathic Itch |
| 10:00am 10:15am | Sensory Testing and Managing a Neuropathic Itch Clinic Speaker: Sarina Elmariah, MD, PhD, MPH |
| 10:15am 10:30am | Novel Insights into Notalgia Paraesthetica and Brachioradial Pruritus: Refining Clinical Profiles and Diagnostics Speaker: Lea-Sophie Stahl, MD |
| 10:30am 10:45am | Generalized itch by intradermal ciguatoxin into the mouse cheek – Investigation of mechanisms Speaker: Raphaele Le Garrec, PharmD, PhD |
| 10:45am 10:55am | Q&A Speakers: All |
Grand Ballroom EFG – 5th Floor | |
| 10:00am 10:55am | Concurrent Session: Basic Itch Beyond Skin |
| 10:00am 10:12am | Nasal and Ear Itch Speaker: Pete Smith, MD, PhD |
| 10:12am 10:32am | Cough is itch of the throat Speaker: Jacky Smith MB, ChB, FRCP, PhD |
| 10:32am 10:47am | A consideration of the relationship between itch and the autonomic nervous system in atopic eczema Speaker: Hiroyuki Murota, MD, PhD |
| 10:47am 10:55am | Q&A Speakers: All |
Buenos Aires Room – 5th Floor | |
| 10:55am 11:05am | Break & Poster Session 5 |
| 10:55am | Development of reinnervated human skin model for in vitro studies on pruritus Speaker: Laurent Misery, MD, PhD |
| 11:00am | Analysis of antipruritic effect of a novel gabapentinoid by NC/Nga mice Speakers: Kosuke Matsuda, MS |
Grand Ballroom ABCD – 5th Floor | |
| 11:05am 12:05pm | Pharma & Patient Prospective |
| 12:00pm 1:30pm | Lunch – 5th Floor |
Grand Ballroom ABCD – 5th Floor | |
| 12:20pm 1:10pm | Itch in AD, PN, and CSU: Underlying Mechanisms and the Role of Type 2 Inflammation Industry Session Sponsored by: Sanofi RegeneronSpeakers: Sarina Elmariah, MD, PhD, MPH; Brian S. Kim, MD, MTR |
Grand Ballroom EFG – 5th Floor | |
| 12:20pm 1:10pm | Scratching the Surface: How Targeting IL-13 Relieves Itch in Patients With Moderate-to-Severe Atopic Dermatitis Industry Session Sponsored by: Leo Pharma |
Grand Ballroom ABCD – 5th Floor | |
| 1:15pm 2:00pm | Plenary Session Genetics of Itch |
| 1:15pm 1:30pm | Role of BNP in Chronic Itch Speaker: Santosh Mishra, PhD |
| 1:30pm 1:45pm | OSM a Mediator of Inflammatory itch Speaker: Mark Hoon, PhD |
| 1:45pm 1:55pm | Single-Soma Deep RNA sequencing of Human DRG Neurons Reveals Novel Molecular and Cellular Mechanisms Underlying Somatosensation Speaker: Wenqin Luo, PhD |
| 1:55pm 2:00pm | Q&A Speakers: All |
Buenos Aires Room – 5th Floor | |
| 2:00pm 2:15pm | Break & Poster Session 6 |
| 2:05pm | Investigating different dimensions of catastrophizing on experimental-induced itch perception in healthy volunteers Speaker: Giulia Erica Aliotta, PhD |
| 2:10pm | Efficacy and Associated Neurotransmitters of Digital Cognitive Behavior Therapy for Atopic Dermatitis: A Comparative Effectiveness Research Speakers: Wanying Zhai, MD, PhD |
Grand Ballroom ABCD – 5th Floor | |
| 2:15pm 3:15pm | Concurrent Session: Unmet needs of Chronic Itch in Ethnic, Geriatric, and Scabies |
| 2:15pm 2:30pm | Redefining paradigms; itch in older adults Speaker: Daniel C. Butler, MD |
| 2:30pm 2:45pm | Itch in Ethnic Populations Speaker: Shawn Kwatra, MD |
| 2:45pm 3:00pm | Itch in Scabies Speaker: Katja Fischer, PhD |
| 3:00pm 3:10pm | Chronic Itch in Elderly: A Cross Sectional Study Speaker: Asit Kumar Mittal, MD |
| 3:10pm 3:15pm | Q&A Speakers: All |
Grand Ballroom EFG – 5th Floor | |
| 2:15pm 3:15pm | Concurrent Session: Epidemiology, Guidelines, and QOL |
| 2:15pm 2:30pm | The European Guideline on Chronic Pruritus: update 2023 Speaker: Elke Weisshaar, MD |
| 2:30pm 2:45pm | Acceptability and perceived benefits of validated pruritus assessment tools Speaker: Manuel Pereira, MD, PhD |
| 2:45pm 3:00pm | Patients with Diabetes Experience Greater Pruritus Burden with Impact on QOL Speaker: Tingwei Zhang, MD |
| 3:00pm 3:10pm | Characteristics and Underlying Factors of Itch in Type 2 Diabetes Mellitus: A Comprehensive Study Speaker: Alexandra A. Stefaniak, MD, PhD |
| 3:10pm 3:15pm | Q&A Speakers: All |
Grand Ballroom ABCD – 5th Floor | |
| 3:20pm 5:10pm | Hot Topics |
| 3:20pm 3:28pm | Barzolvolimab demonstrates safety and clinically meaningful activity in moderate-severe prurigo nodularis Speaker: Martin Metz, MD |
| 3:28pm 3:36pm | Sustained release kappa opioid receptor agonist subdermal implant for the treatment of chronic pruritus Speaker: Tyler C. Beck, PhD |
| 3:36pm 3:44pm | Histamine – and Pruritogen-induced Itch is Inhibited by a TRPM8 Agonist in Humans Speaker: Hye One Kim, MD, PhD |
| 3:44pm 3:52pm | Unraveling the key role of TSLP and TRPV4 in dry skin-induced pruritus: insights into cutaneous neuroimmune interactions Speaker: Won-Sik Shim, PhD |
| 3:52pm 4:00pm | Environmental Influences on Induction of Itching and Scratching Using Immersive Virtual Reality Speaker: Emmy van de Burgt, MSc |
| 4:00pm 4:08pm | Staphylococcus aureus protease-driven epidermal barrier disruption and neurogenic skin inflammation Speaker: Yanek Jiménez-Andrade, PhD |
| 4:08pm 4:16pm | INM-755 cannabinol cream demonstrates anti-itch activity in patients with epidermolysis bullosa Speaker: Alexandra Mancini, MSc |
| 4:16pm 4:24pm | Scratching induces dysinnervation and local hypersensitivity in chronic pruritus patients Speaker: Konstantin Agelopoulos, PhD |
| 4:24pm 4:32pm | Evaluating the safety and efficacy of topical KM-001, a TRPV3 inhibitor, for treatment of pruritus in patients with Lichen Simplex Chronicus (LSC): a first in human (FIH), double-blind, randomized vehicle-controlled study Speaker: Shelly Leibman Barak, MSc |
| 4:32pm 4:40pm | Loss of claudin-1 on keratinocytes induces itch transmitted by multiple types of sensory nerves Speaker: Susumu Toshima, MD |
| 4:40pm 4:48pm | Mechanisms to Drive Internal Itch Inhibitory System Speaker: Tasuku Akiyama, PhD |
| 4:48pm 5:06pm | Worldwide Study on the Prevalence of Itch: Examining Itch as a Global Health Problem Speaker: Gil Yosipovitch, MD |
Grand Ballroom ABCD – 5th Floor | |
| 5:06pm 5:20pm | Closing Ceremony Chair: Elke Weisshaar, MD |